[HTML][HTML] IL-17+ CD8+ T cells: differentiation, phenotype and role in inflammatory disease
The pro-inflammatory cytokine interleukin-17A (IL-17) has been the subject of research by
many groups worldwide. IL-17 expression is often associated with a specific subset of CD4+
T cells (the so-called Th17 cells); however various other immune cell subsets can also
synthesise and express IL-17, including CD8+ T cells. Here we review recent data regarding
the presence of IL-17+ CD8+ T cells (also known as Tc17 cells) in human inflammatory
disease, discuss current knowledge regarding the culture conditions required for the …
many groups worldwide. IL-17 expression is often associated with a specific subset of CD4+
T cells (the so-called Th17 cells); however various other immune cell subsets can also
synthesise and express IL-17, including CD8+ T cells. Here we review recent data regarding
the presence of IL-17+ CD8+ T cells (also known as Tc17 cells) in human inflammatory
disease, discuss current knowledge regarding the culture conditions required for the …
