A growing body of evidence suggests that angiogenesis plays a crucial role in the
pathogenesis of multiple sclerosis (MS). Animal models of MS show a significant
improvement when the process of angiogenesis is halted. In this study, we measured the
serum levels of vascular–endothelial growth factor (VEGF), soluble Endoglin (sEng),
angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2), and uric acid (UA) as well as serum anti-
Epstein–Barr virus (EBV) EBNA-1 IgG in 50 MS patients (including 20 newly diagnosed and …