[HTML][HTML] Methods in mammalian autophagy research

N Mizushima, T Yoshimori, B Levine - Cell, 2010 - cell.com
Cell, 2010cell.com
Autophagy has been implicated in many physiological and pathological processes.
Accordingly, there is a growing scientific need to accurately identify, quantify, and
manipulate the process of autophagy. However, as autophagy involves dynamic and
complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to
monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian
macroautophagy.
Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.
cell.com