Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics

MIF Shariff, IJ Cox, AI Gomaa, SA Khan… - Expert review of …, 2009 - Taylor & Francis
MIF Shariff, IJ Cox, AI Gomaa, SA Khan, W Gedroyc, SD Taylor-Robinson
Expert review of gastroenterology & hepatology, 2009Taylor & Francis
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death
worldwide and, owing to changes in the prevalence of the two major risk factors, hepatitis B
virus and hepatitis C virus, its overall incidence remains alarmingly high in the developing
world and is steadily rising across most of the developed world. Early diagnosis remains the
key to effective treatment and there have been recent advances in both the diagnosis and
therapy of HCC, which have made important impacts on the disease. This review outlines …
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide and, owing to changes in the prevalence of the two major risk factors, hepatitis B virus and hepatitis C virus, its overall incidence remains alarmingly high in the developing world and is steadily rising across most of the developed world. Early diagnosis remains the key to effective treatment and there have been recent advances in both the diagnosis and therapy of HCC, which have made important impacts on the disease. This review outlines the epidemiological trends, risk factors, diagnostic developments and novel therapeutics for HCC, both in the developing and developed world.
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