[HTML][HTML] Functional analysis of activating receptor LMIR4 as a counterpart of inhibitory receptor LMIR3

K Izawa, J Kitaura, Y Yamanishi, T Matsuoka… - Journal of Biological …, 2007 - ASBMB
The leukocyte mono-Ig-like receptor (LMIR) belongs to a new family of paired
immunoreceptors. In this study, we analyzed activating receptor LMIR4/CLM-5 as a
counterpart of inhibitory receptor LMIR3/CLM-1. LMIR4 is expressed in myeloid cells,
including granulocytes, macrophages, and mast cells, whereas LMIR3 is more broadly
expressed. The association of LMIR4 with Fc receptor-γ among immunoreceptor tyrosine-
based activation motif-bearing molecules was indispensable for LMIR4-mediated functions …