Constituting a part of the innate immune system, the complement system consists of over 50
proteins either acting as part of a 3-branch activation cascade, a well-differentiated
regulatory system in fluid phase or on each tissue, or as receptors translating the activation
signal to multiple cellular effector functions. Complement serves as first line of defence
against infections from bacteria, viruses and parasites by orchestrating the immune
response through opsonisation, recruitment of immune cells to the site of infection and direct …