Sodium chloride coupled transport in mammalian nephrons

M Burg, D Good - Annual review of physiology, 1983 - annualreviews.org
M Burg, D Good
Annual review of physiology, 1983annualreviews.org
Mammalian nephrons filter large amounts of sodium chloride. Under nor mal conditions they
reabsorb. virtually all. ofit, and only a fraction of a percent appears in the urine. The para11el
reabsorption of sodium and chloride is one of the principal functions of the nephron.
Although there is convincing evidence that primary active sodium transport couples cellu lar
energy to transport of sodium chloride and other substances in renal tubules, there is no
evidence of any primary active chloride transport.
Mammalian nephrons filter large amounts of sodium chloride. Under nor mal conditions they reabsorb. virtually all. ofit, and only a fraction of a percent appears in the urine. The para11el reabsorption of sodium and chloride is one of the principal functions of the nephron. Although there is convincing evidence that primary active sodium transport couples cellu lar energy to transport of sodium chloride and other substances in renal tubules, there is no evidence of any primary active chloride transport.
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