Recurrent chromosomal abnormalities, especially chromosomal translocations, are strongly
associated with certain subtypes of leukemia, lymphoma and solid tumors. The appearance
of particular translocations or associated genomic alterations can be important indicators of
disease prognosis, and in some cases, certain translocations may indicate appropriate
therapy protocols. To date, most of our knowledge about chromosomal translocations has
derived from characterization of the highly selected recurrent translocations found in certain …