PTH and PTHrP signaling in osteoblasts
NS Datta, AB Abou-Samra - Cellular signalling, 2009 - Elsevier
NS Datta, AB Abou-Samra
Cellular signalling, 2009•ElsevierThe striking clinical benefit of PTH in osteoporosis began a new era of skeletal anabolic
agents. Several studies have been performed, new studies are emerging out and yet
controversies remain on PTH anabolic action in bone. This review focuses on the molecular
aspects of PTH and PTHrP signaling in light of old players and recent advances in
understanding the control of osteoblast proliferation, differentiation and function.
agents. Several studies have been performed, new studies are emerging out and yet
controversies remain on PTH anabolic action in bone. This review focuses on the molecular
aspects of PTH and PTHrP signaling in light of old players and recent advances in
understanding the control of osteoblast proliferation, differentiation and function.
The striking clinical benefit of PTH in osteoporosis began a new era of skeletal anabolic agents. Several studies have been performed, new studies are emerging out and yet controversies remain on PTH anabolic action in bone. This review focuses on the molecular aspects of PTH and PTHrP signaling in light of old players and recent advances in understanding the control of osteoblast proliferation, differentiation and function.
Elsevier