The role of genomic instability in the pathogenesis of squamous cell carcinoma of the head and neck

SM Wiseman, DL Stoler… - Surgical Oncology …, 2004 - surgonc.theclinics.com
Human beings are composed of a highly complex community of cells, and each cell type has
its own role that is defined by the genetic instructions it expresses. For cells to function
normally, their genetic instructions must be accurately transmitted from one generation to the
next. The information carried by the genetic code must be accurately replicated and
efficiently repaired to ensure the survival of cells, organisms, and species. In humans, the
importance of maintaining the integrity of their genetic blueprint can be appreciated by the …