Wound repair in the context of extracellular matrix

J Gailit, RAF Clark - Current opinion in cell biology, 1994 - Elsevier
J Gailit, RAF Clark
Current opinion in cell biology, 1994Elsevier
Wound repair requires a continually evolving network of interactions among cells, cytokines
and the extracellular matrix. Cell-surface integrins provide a mechanical connection
between matrix components and the cytoskeleton, and integrins can transduce an
astonishing variety of signals along pathways that may intercept the pathways triggered by
cytokine receptors.
Abstract
Wound repair requires a continually evolving network of interactions among cells, cytokines and the extracellular matrix. Cell-surface integrins provide a mechanical connection between matrix components and the cytoskeleton, and integrins can transduce an astonishing variety of signals along pathways that may intercept the pathways triggered by cytokine receptors.
Elsevier