Hypofractionated intensity-modulated radiotherapy (70 Gy at 2.5 Gy per fraction) for localized prostate cancer: Cleveland Clinic experience

PA Kupelian, TR Willoughby, CA Reddy… - International Journal of …, 2007 - Elsevier
Purpose: To study the outcomes in patients treated for localized prostate cancer with 70 Gy
delivered at 2.5-Gy/fraction within 5 weeks. Methods and Materials: The study sample
included all 770 consecutive patients with localized prostate cancer treated with
hypofractionated intensity-modulated radiotherapy at the Cleveland Clinic between 1998
and 2005. The median follow-up was 45 months (maximum, 86). Both the American Society
for Therapeutic Radiology and Oncology (ASTRO) biochemical failure definition and the …