The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein …
A Boullier, KL Gillotte, S Hörkkö, SR Green… - Journal of Biological …, 2000 - ASBMB
There is growing evidence that CD36 has an important physiological function in the uptake
of oxidized low density lipoprotein (OxLDL) by macrophages. However, the ligand specificity
and the nature of the ligands on OxLDL that mediate the binding to CD36 remain ill defined.
Results from recent studies suggested that some of the macrophage scavenger receptors
involved in the uptake of OxLDL recognized both the lipid and the protein moieties of
OxLDL, but there was no conclusive direct evidence for this. The present studies were …
of oxidized low density lipoprotein (OxLDL) by macrophages. However, the ligand specificity
and the nature of the ligands on OxLDL that mediate the binding to CD36 remain ill defined.
Results from recent studies suggested that some of the macrophage scavenger receptors
involved in the uptake of OxLDL recognized both the lipid and the protein moieties of
OxLDL, but there was no conclusive direct evidence for this. The present studies were …
