Gene-expression signatures in breast cancer
C Sotiriou, L Pusztai - New England Journal of Medicine, 2009 - Mass Medical Soc
New England Journal of Medicine, 2009•Mass Medical Soc
This review discusses the results of DNA microarray signatures in breast cancer. These
signatures have been useful in the classification of breast cancers, and they have an
association with clinical outcomes. Surprisingly, there is little overlap in the types of genes
among several useful microarray signatures. The true value of these signatures will become
apparent only when prospective trials, now in progress, have been completed.
signatures have been useful in the classification of breast cancers, and they have an
association with clinical outcomes. Surprisingly, there is little overlap in the types of genes
among several useful microarray signatures. The true value of these signatures will become
apparent only when prospective trials, now in progress, have been completed.
This review discusses the results of DNA microarray signatures in breast cancer. These signatures have been useful in the classification of breast cancers, and they have an association with clinical outcomes. Surprisingly, there is little overlap in the types of genes among several useful microarray signatures. The true value of these signatures will become apparent only when prospective trials, now in progress, have been completed.
The New England Journal Of Medicine