[HTML][HTML] Long-term survival of human spermatogonial stem cells in mouse testes
M Nagano, P Patrizio, RL Brinster - Fertility and sterility, 2002 - Elsevier
OBJECTIVE: To evaluate colonizing ability of human spermatogonial stem cells in mouse
testes. DESIGN: Transplantation of human testis cells into the seminiferous tubules of
immunodeficient mice. SETTING: University hospital and academic laboratory. PATIENT (S):
Men with obstructive azoospermia or maturation arrest of spermatogenesis. INTERVENTION
(S): Analyzed up to 6 months after transplantation. Also analyzed: cryopreservation of donor
cells, donor cell concentrations, and leuprolide treatment of recipients. MAIN OUTCOME …
testes. DESIGN: Transplantation of human testis cells into the seminiferous tubules of
immunodeficient mice. SETTING: University hospital and academic laboratory. PATIENT (S):
Men with obstructive azoospermia or maturation arrest of spermatogenesis. INTERVENTION
(S): Analyzed up to 6 months after transplantation. Also analyzed: cryopreservation of donor
cells, donor cell concentrations, and leuprolide treatment of recipients. MAIN OUTCOME …