Congestive heart failure: pathophysiologic consequences of neurohormonal activation and the potential for recovery: part II

P Dube, KT Weber - The American journal of the medical sciences, 2011 - Elsevier
The congestive heart failure syndrome has its pathophysiologic origins rooted in
neurohormonal activation, including hormone-mediated salt and water retention with
ensuing central and systemic venous congestion. A systemic illness involving soft tissues
and bone compounds this syndrome. Despite its complexity, however, many of these
pathophysiologic consequences may prove reversible. Several lines of evidence, including
responses to bed rest, pharmaceuticals and circulatory assist devices, suggest the potential …