Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissue
DJ Ceradini, GC Gurtner - Trends in cardiovascular medicine, 2005 - Elsevier
The identification of bone marrow-derived endothelial progenitor cells has altered our
understanding of new blood vessel growth and tissue regeneration. Previously, new blood
vessel growth in the adult was thought to only occur through angiogenesis, the sprouting of
new vessels from existing structures. However, it has become clear that circulating bone
marrow-derived cells can form new blood vessels through a process of postnatal
vasculogenesis, with endothelial progenitor cells selectively recruited to injured or ischemic …
understanding of new blood vessel growth and tissue regeneration. Previously, new blood
vessel growth in the adult was thought to only occur through angiogenesis, the sprouting of
new vessels from existing structures. However, it has become clear that circulating bone
marrow-derived cells can form new blood vessels through a process of postnatal
vasculogenesis, with endothelial progenitor cells selectively recruited to injured or ischemic …