Neurotoxic effect of lead at low concentrations
O Mameli, MA Caria, F Melis, A Solinas, C Tavera… - Brain Research …, 2001 - Elsevier
The effects of lead exposure at low concentrations were evaluated by studying the post-
rotatory nystagmus (PRN) in two groups of rats exposed for 3 months to 50 parts per million
(ppm) of sodium acetate and 50 ppm of lead acetate, respectively, in the drinking water. Only
animals treated with lead acetate showed changes of the PRN parameters which were
significantly related to the concentration of lead in the blood and in brain structures. The
patterns of PRN responses were characterized and classified into four types: progressively …
rotatory nystagmus (PRN) in two groups of rats exposed for 3 months to 50 parts per million
(ppm) of sodium acetate and 50 ppm of lead acetate, respectively, in the drinking water. Only
animals treated with lead acetate showed changes of the PRN parameters which were
significantly related to the concentration of lead in the blood and in brain structures. The
patterns of PRN responses were characterized and classified into four types: progressively …
