[HTML][HTML] Protein tyrosine phosphatases in the human genome
A Alonso, J Sasin, N Bottini, I Friedberg, I Friedberg… - Cell, 2004 - cell.com
Cell, 2004•cell.com
Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by
90 genes in the human genome. Here, we present the set of 107 genes in the human
genome that encode members of the four protein tyrosine phosphatase (PTP) families. The
four families of PTPases, their substrates, structure, function, regulation, and the role of these
enzymes in human disease will be discussed.
90 genes in the human genome. Here, we present the set of 107 genes in the human
genome that encode members of the four protein tyrosine phosphatase (PTP) families. The
four families of PTPases, their substrates, structure, function, regulation, and the role of these
enzymes in human disease will be discussed.
Abstract
Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by 90 genes in the human genome. Here, we present the set of 107 genes in the human genome that encode members of the four protein tyrosine phosphatase (PTP) families. The four families of PTPases, their substrates, structure, function, regulation, and the role of these enzymes in human disease will be discussed.
cell.com
