Family history as a risk factor for pelvic organ prolapse
MT McLennan, JK Harris, B Kariuki, S Meyer - International Urogynecology …, 2008 - Springer
MT McLennan, JK Harris, B Kariuki, S Meyer
International Urogynecology Journal, 2008•SpringerThe aim of this study was to determine whether a family history of prolapse and/or hernia is a
risk factor for prolapse. A cohort of 458 women seeking gynecological care was classified as
exposed (family history) or unexposed (without family history). We used χ 2 to assess
confounding and logistic regression to determine risk. Nearly half (47.3%) of the 458
participants reported a positive family history. Of these, 52.5% had prolapse. This was
significantly higher than the 28.9% rate of prolapse in women without a family history (p< …
risk factor for prolapse. A cohort of 458 women seeking gynecological care was classified as
exposed (family history) or unexposed (without family history). We used χ 2 to assess
confounding and logistic regression to determine risk. Nearly half (47.3%) of the 458
participants reported a positive family history. Of these, 52.5% had prolapse. This was
significantly higher than the 28.9% rate of prolapse in women without a family history (p< …
Abstract
The aim of this study was to determine whether a family history of prolapse and/or hernia is a risk factor for prolapse. A cohort of 458 women seeking gynecological care was classified as exposed (family history) or unexposed (without family history). We used χ 2 to assess confounding and logistic regression to determine risk. Nearly half (47.3%) of the 458 participants reported a positive family history. Of these, 52.5% had prolapse. This was significantly higher than the 28.9% rate of prolapse in women without a family history (p < 0.001). The crude risk ratio for family history of prolapse and/or hernia and prolapse was 1.8 (95% CI 1.4–2.3). After adjusting for vaginal deliveries, incontinence, and hysterectomy, the risk of prolapse was 1.4 (95% CI 1.2–1.8) times higher in women with a family history of prolapse and/or hernia. Heredity is a risk factor for prolapse. History taking should include both male and female family members.
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