B-cell epitopes as a screening instrument for persistent cow's milk allergy
KM Järvinen, K Beyer, L Vila, P Chatchatee… - Journal of allergy and …, 2002 - Elsevier
Background: Cow's milk is one of the most common causes of food allergy in the first years
of life. We recently defined IgE-binding epitopes of all 6 major cow's milk proteins (αs1-, αs2-
, β-, and κ-casein; α-lactalbumin; and β-lactoglobulin) and had some evidence suggesting
that IgE antibodies from patients with persistent cow's milk allergy (CMA) recognize different
epitopes on cow's milk proteins than do those from patients who were likely to outgrow their
allergy. Objective: In this study we sought to assess whether recognition of IgE antibodies of …
of life. We recently defined IgE-binding epitopes of all 6 major cow's milk proteins (αs1-, αs2-
, β-, and κ-casein; α-lactalbumin; and β-lactoglobulin) and had some evidence suggesting
that IgE antibodies from patients with persistent cow's milk allergy (CMA) recognize different
epitopes on cow's milk proteins than do those from patients who were likely to outgrow their
allergy. Objective: In this study we sought to assess whether recognition of IgE antibodies of …