Novel human secreted phospholipase A2 with homology to the group III bee venom enzyme
E Valentin, F Ghomashchi, MH Gelb… - Journal of Biological …, 2000 - ASBMB
Venom and mammalian secreted phospholipases A 2 (sPLA 2 s) have been associated with
numerous physiological, pathological, and toxic processes. So far, structurally related group
I and II sPLA 2 s have been found in vertebrates such as mammals and snakes, whereas
group III sPLA 2 s have mainly been found in venom from invertebrates such as bees and
scorpions. Here we report the cloning and expression of a cDNA coding for a human group
III (hGIII) sPLA 2. The full-length cDNA codes for a signal peptide of 19 residues followed by …
numerous physiological, pathological, and toxic processes. So far, structurally related group
I and II sPLA 2 s have been found in vertebrates such as mammals and snakes, whereas
group III sPLA 2 s have mainly been found in venom from invertebrates such as bees and
scorpions. Here we report the cloning and expression of a cDNA coding for a human group
III (hGIII) sPLA 2. The full-length cDNA codes for a signal peptide of 19 residues followed by …
