One early phase of atherosclerosis involves the recruitment of inflammatory cells from the
circulation and their transendothelial migration. This process is predominantly mediated by
cellular adhesion molecules, which are expressed on the vascular endothelium and on
circulating leukocytes in response to several inflammatory stimuli. Selectins (P, E and L) and
their ligands (mainly P-selectin ligand) are involved in the rolling and tethering of leukocytes
on the vascular wall. Intercellular adhesion molecules (ICAMs) and vascular cell adhesion …