Despite its importance in terms of energy homeostasis, the role of AMP-activated protein
kinase in adipose tissue remains controversial. Initial studies have described an anti-lipolytic
role for AMP-activated protein kinase, whereas more recent studies have suggested the
converse. Thus we have addressed the role of AMP-activated protein kinase in adipose
tissue by modulating AMP-activated protein kinase activity in primary rodent adipocytes
using pharmacological activators or by adenoviral expression of dominant negative or …