Mechanism of genome transcription in segmented dsRNA viruses

JA Lawton, MK Estes, BVV Prasad - 2000 - Elsevier
Publisher Summary This chapter discusses the mechanism of genome transcription in
segmented double-stranded RNA (dsRNA) viruses. Genome transcription is a critical stage
in the life cycle of a virus, as this is the process by which the viral genetic information is
presented to the host cell protein-synthesis machinery for the production of the viral proteins
needed for genome replication and progeny virion assembly. Viruses with dsRNA genomes
face a particular challenge in that host cells do not produce proteins that can transcribe from …