[CITATION][C] The SCID-hu xenogeneic transplantation model allows screening of anti-psoriatic drugs
WH Boehncke, M Kock, K Hardt-Weinelt… - Archives of …, 1999 - Springer
WH Boehncke, M Kock, K Hardt-Weinelt, M Wolter
Archives of dermatological research, 1999•SpringerM. Kock Animal Research Faculty, Frankfurt University Medical School, Frankfurt am Main,
Germany tained with dexamethasone (Table 1). However, the grafts retained all
characteristics of lesional psoriatic skin as seen in the negative controls. This report
documents that the phenotype of lesional psoriatic skin is reversible in the SCID-hu
xenogeneic transplantation model. Steroids have their place in the treatment of psoriasis,
although systemic application should be used with great caution. Thus, efficacy of oral …
Germany tained with dexamethasone (Table 1). However, the grafts retained all
characteristics of lesional psoriatic skin as seen in the negative controls. This report
documents that the phenotype of lesional psoriatic skin is reversible in the SCID-hu
xenogeneic transplantation model. Steroids have their place in the treatment of psoriasis,
although systemic application should be used with great caution. Thus, efficacy of oral …
M. Kock Animal Research Faculty, Frankfurt University Medical School, Frankfurt am Main, Germany tained with dexamethasone (Table 1). However, the grafts retained all characteristics of lesional psoriatic skin as seen in the negative controls. This report documents that the phenotype of lesional psoriatic skin is reversible in the SCID-hu xenogeneic transplantation model. Steroids have their place in the treatment of psoriasis, although systemic application should be used with great caution. Thus, efficacy of oral dexamethasone treatment in this animal model is not surprising.
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