Schistosoma mansoni: eosinophilia and the development of lymphocyte blastogenesis in response to soluble egg antigen in inbred mice
DG Colley - Experimental Parasitology, 1972 - Elsevier
Mice of four inbred strains (A/J, C/57BL/6J, CBA/J, BALB/c) were compared as definitive
hosts of Schistosoma mansoni. All four strains allowed the maturation of adult worms, but the
percentage of recovery of mature worms varied widely according to strain (A/J, 36%,
C/57BL/6J, 42%; CBA/J, 58%; BALB/c, 78%). The cell-mediated immune response of these
mice to a soluble schistosomal egg antigen was determined by in vitro lymphocyte
blastogenesis during the course of the infection. All strains exhibited this response by 1 1 2 …
hosts of Schistosoma mansoni. All four strains allowed the maturation of adult worms, but the
percentage of recovery of mature worms varied widely according to strain (A/J, 36%,
C/57BL/6J, 42%; CBA/J, 58%; BALB/c, 78%). The cell-mediated immune response of these
mice to a soluble schistosomal egg antigen was determined by in vitro lymphocyte
blastogenesis during the course of the infection. All strains exhibited this response by 1 1 2 …
