[PDF][PDF] Apoptosis: telling cells their time is up

S Nagata - Current Biology, 1996 - cell.com
Current Biology, 1996cell.com
Ligand engagement by the receptor Fas leads to apoptosis. A clue to how this happens
comes from the discovery that ligand binding leads to recruitment to Fas of a protease,
homologous to interleukin-1β converting enzyme, likely to initiate a proteolytic cascade that
drives apoptosis.
Abstract
Ligand engagement by the receptor Fas leads to apoptosis. A clue to how this happens comes from the discovery that ligand binding leads to recruitment to Fas of a protease, homologous to interleukin-1β converting enzyme, likely to initiate a proteolytic cascade that drives apoptosis.
cell.com